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FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology, 35 (5), e21526
[5] Two honest caveats sit on top of those numbers
Cell Metabolism Reynolds et al
Dose adjustments in older adults typically involve starting at the lower end of the range (100 to 150 mcg per injection) and titrating based on IGF-1 response and tolerability, given that baseline GH reserve is lower and water-retention side effects may be more symptomatic in older patients with pre-existing cardiovascular conditions
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