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All information comes from the preclinical literature and is provided for scientific and informational purposes

For context, the FDA-approved finished drug versions of semaglutide include brand names like Ozempic and Wegovy (registered trademarks of Novo Nordisk), and the FDA-approved finished drug versions of tirzepatide include Zepbound and Mounjaro (registered trademarks of Eli Lilly)

Policy changes like the Inflation Reduction Acts $2,000 out-of-pocket (OOP) cap for Medicare Part D beneficiaries may offer some relief, as patients who reach the cap pay $0 thereafter, but they also risk prompting payers to tighten coverage for high-cost drugs, especially those indicated for obesity

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Unlike treatments like insulin, which require timing around meals, the goal [of Ozempic] is to establish a steady state in the body over time