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Scott RD et al

This results in IGF1-LR3 remaining in the bloodstream 120 times longer than IGF-1

Interestingly, direct injections of Ex-4 into the gustatory cortex of mice maintained on a high-fat diet reduced intake only when the fat density of the test diet differed from that of the maintenance diet, regardless of whether the shift was from high- to low-fat or low- to high-fat relative to the maintenance diet

Evidence-based recommendations are critical to ensure the safe and efficient use of these medications in the treatment of obesity as their use continues to increase

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