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The findings may have clinical implicationsespecially since the team also found that breast cancer samples from patients whose disease had spread to the lung showed elevated SLC25A39, and that higher SLC25A39 expression was strongly correlated with poorer overall survival in breast cancer patients

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134 The NLRP3 is also upregulated resulting from activated NF-B, and activates caspase 1 which induces cell pyroptosis, a type of programmed cell death characterized by the formation of pores in the plasma membrane, leading to the release of proinflammatory cytokines and subsequent cell lysis 38,135 (Fig

They offer only a snapshot rather than a history of nutritional status