Remington G, Addington D, Honer W, Ismail Z, Raedler T, Teehan M
The functional status of p53, in combination with other molecular markers, such as oestrogen and progesterone receptors, B-cell lymphoma 2 (Bcl-2), BCL2-associated X (Bax), and human epidermal growth factor receptor 2 (HER-2), provides insight into tumour proliferative capacity and replicative potential, making it a critical mechanistic hub in breast cancer biology (4345)
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Finally, transfected neurons were immunostained for presynaptic markers, VGLUT1 and synapsin, and postsynaptic marker, PSD-95, to assess functional synapse formation