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In terms of iron uptake, diabetic conditions increase the expression of ZRT/IRT-like protein 14 (ZIP14), divalent metal transporter 1 (DMT1), and transferrin receptor 1 (TFR1)
All dosage information is for research reference only
It also directly confirms that regulating the ferroptosis pathway (improving the endogenous iron metabolism and anti-lipid peroxidation metabolism of osteoblasts) can protect the mitochondrial structure of osteoblasts damaged by ferroptosis (101)
Tumor-imposed metabolic restrictions can mediate T cell hyporesponsiveness during cancer
It was first described in 1998
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