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1 2 3 4 5 6 7 8 9 10 11 12 Roberts and Hedges' clinical procedures in emergency medicine and acute care (7th ed.)

These processes play key roles to promote chemoresistance in tumors, where elevated GSH inactivates electrophilic chemotherapeutic agents (cisplatin, alkylators), GSTs enable drug conjugation, and MRP-catalyzed efflux reduces intracellular drug levels - while inhibiting therapy-induced oxidative stress at the same time

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The secretion of endogenous human growth hormone is associated with benefits such as bone formation, enhanced tissue repair, and improved cognitive function

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