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Approval is never automatic

While these effects are strongest when you first start semaglutide, and when you increase your dosage, and tend to settle down when you're on a stable dose, they can spike when you take your weekly shot

Bogunovic M, Dav SH, Tilstra JS, Chang DT, Harpaz N, Xiong H, et al

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Women who are planning to conceive should avoid or discontinue Semaglutide at least 2 months before trying to get pregnant , due to its long half-life