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Regarding resorcinol, and more specifically 4-hexyl resorcinol (4-HR), its anti-melanogenic effect has been confirmed in a recent double-blind clinical trial in which volunteers received either a 3% niacinamide formulation or a 3% niacinamide formulation coupled with 0.4% 4-HR

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With oral contraceptives, you can: Make your period come faster : Stop taking the pill containing hormones or switch to the placebo pill (the pills in the pack containing no contraceptive)

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The safety record is generally placebo-like, but several specific findings deserve attention