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Evidence shows that a decline in serum Klotho level occurs in early chronic kidney disease (CKD) and continues as CKD progresses
In addition, one of the oldest drug classes for diabetes treatment, sulfonylureas, contributes to substantial weight gain of 0.6 to 1.8 kg, depending on the type of insulin secretagogues (lower risk with meglitinides) and length of treatment
Severe, persistent fatigue
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Apoptosis 20, 12961306
