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Curr Biol 15:702713 Ma XM, Blenis J (2009) Molecular mechanisms of mTOR-mediated translational control

Although the concurrence of inflammation, oxidative stress, and immune system alterations in the systemic compartment of ALS patients needs elucidation, the present study supports the notion that monitoring dynamic changes of humoral effectors during disease progression may further our understanding of pathological alterations in ALS

These findings have led to the hypothesis that basal levels of autophagy are required for the pluripotency acquired by CSCs

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