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Yes, dietary changes are likely to have the greatest effect on increasing GLP-1 levels

doi:10.1007/s00018-005-5163-7

Across neural cell models, spinal cord injury paradigms, and aged rodent cognition studies, a consistent pattern has emerged: GHK-Cu upregulates neurotrophic factors, suppresses neuroinflammation through NF-kB pathway blockade, and modulates gene expression networks that deteriorate in neurodegenerative contexts

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When used with insulin or sulfonylureas, they may increase the risk of hypoglycaemia, and dose adjustments of these medications may be necessary