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Managing side effects during dose escalation Gastrointestinal side effects are the most commonly reported adverse events with retatrutide, and they peak during the dose escalation period

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While these findings indicate intriguing research possibilities, ongoing exploration is required to clarify the full scope of these mechanisms

Estrogen deficiency and the decline of skin collagen were first observed in 1941 by Albright, who noticed that thin skin was more common in older women with osteoporotic fractures [21]

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