Such mechanisms could detrimentally impair astrocyte functions either through the loss or down-regulation of essential homoeostatic functions or through the gain of detrimental effects, or combinations of both
Moreover, glucuronidation activity was also detected in other tissues such as kidney (Sutherland et al., 1993), brain (King et al.,1999), or placenta (Collier et al., 2002)
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Table 3 Multivariate models for discontinuation patterns and switch burden In this retrospective study we identified significant variability in GLP-1RA tolerance and discontinuation patterns among individuals with IBS
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