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Prompt identification and correction of the cause of hyperglycemia or ketosis is necessary
About 7.5% of patients had vitamin D deficiency within 6 months, and this grew to 13.6% (approximately 1 in 7 patients) after 12 months
Many improvements in cardiometabolic markers also reverted toward baseline after treatment ended
To assess the associations of semaglutide with incident AUD (first time diagnosis of AUD), the study population included 83,825 patients who had active medical encounters for the diagnosis of obesity in 6/202112/2022, were for the first time (new-user design) prescribed semaglutide or non-GLP-1RA anti-obesity medications (naltrexone, topiramate, bupropion, orlistat, phentermine) 54 during 6/202112/2022 (time zero or index event), had no diagnosis of AUD on or before the index event and had a diagnosis of at least one of obesity-associated comorbidities (T2D, hypertension, hypercholesterolemia, hyperlipidemia, heart diseases, stroke) on or before the index event
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