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Boldine is a primary aporphine alkaloid derived from the leaves and bark of Peumus boldus Molina [Monimiaceae] (Fuentes-Barros et al., 2023)

Fournier M, Monin A, Ferrari C, Baumann PS, Conus P, Do K

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Moreover, inhibition of RIP1 by a specific RIP1 inhibitor protected against HFD-induced hepatic steatosis, inflammation and fibrosis in mice [95]