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Side Effects by Dose (SURMOUNT-1 Data) Management Strategies Nausea Eat smaller, more frequent meals Avoid fatty, greasy, or spicy foods, especially early in treatment Stop eating at the first sign of fullness Ginger tea, ginger supplements, or ginger candies Stay well-hydrated, as dehydration worsens nausea Consider slower titration if persistent Constipation Increase fiber intake gradually (vegetables, fruits, whole grains) Drink plenty of water

When CKD reaches an advanced stage, dangerous levels of fluid, electrolytes, and wastes can build up in the body