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GIP receptor (present in retatrutide and tirzepatide, absent in survodutide): Glucose-dependent insulinotropic polypeptide (GIP) enhances insulin secretion in a glucose-dependent manner, promotes nutrient uptake and lipid metabolism in adipose tissue, and may improve adipose tissue remodeling
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Streptozotocin (STZ) is a glucosaminenitrosourea compound that selectively destroys pancreatic -cells and is widely used to induce experimental diabetes models
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