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Jongkees, B
In: Hand MS et al, editors
Simon MC, Strassburger K, Nowotny B, Kolb H, Nowotny P, Burkart V, et al
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At present, the mechanism of CR promoting autophagy and anti-aging has not been fully studied, but it is mainly divided into two aspects: on the one hand, it achieves the purpose of anti-aging by reducing the levels of glucose and insulin, and on the other hand, it exerts the effect of promoting longevity by regulating multiple signaling pathways in cells, including AMP-activated protein kinase (AMPK), mammalian target of rapamycin (mTOR) and Sirtuins
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