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BCL2 like 13 (BCL2L13), originally described as a pro-apoptotic member of the BCL2 protein family, contains all conserved BH domains: BH1, BH2, BH3, and BH4, as well as two LIR domains [153]

The most common early indicator is reduced shedding

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But this category is another example where the claims are outpacing the actual evidence