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A typical aggressive protocol might use 0.75mg daily for the first three days, 0.5mg for days four through seven, then 0.25mg to 0.5mg for the remainder of treatment

In both of those cases, you can add fortified foods to your diet or take supplements to meet this need

There is zero evidence that regular high doses of B12 cause liver toxicity in any way, shape or form

Every vial is third-party tested by independent laboratories to verify 99% HPLC purity, amino acid identity by mass spectrometry, and endotoxin limits by LAL testing, and ships with a batch-specific certificate of analysis published on our COA page

PMID 8440794