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A multi-receptor peptide studied for activity across GLP-1, GIP, and glucagon pathways, used in metabolic and endocrine signaling research

Vaith P, Assmann G, Uhlenbruck G

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In this Article we use a set of 125 experimentally characterized glucagon and GLP-1 peptide analogues to train models that capture the relationship between peptide sequence and agonism or receptor activation at both the GCGR and GLP-1R