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When someone applies for life insurance after losing weight on GLP-1 medications, underwriters see what looks like a healthy person with: Normal BMI Improved blood pressure Better cholesterol levels Lower HbA1c levels But here's the catch: Research from the landmark STEP 1 trial extension shows that participants regain approximately two-thirds of their prior weight loss within one year of stopping semaglutide (Wilding et al., 2022)
FLOW (A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease) was a Phase 3b kidney outcomes trial enrolling 3,533 adults with type 2 diabetes and CKD
Roche, Switzerland)
Ask about the titration protocol and what to expect during the first four to six weeks of treatment
(62(2)):575-593 doi:10.1007/s10528-023-10490-x
