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The GABA-A receptors (GABRA family of genes) are the most abundant and present throughout the central nervous system (brain, spinal cord)
Constipation is typically more common during dose initiation and escalation periods
There was a reduction in the expression of JNK-1 (C- Jun N- terminal kinases), TLR-2 (Toll- like receptor 2) and TLR-4 at mRNA (messenger ribonucleic acid) and protein level
To verify this hypothesis, we perform a model reaction between TPE-DCV and a thiol, 2-mercaptoethanol (ME)
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