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This approach is appropriate as it accounts for both within-study and between-study heterogeneity, allowing for more generalized conclusions that consider differences in study populations, interventions, and outcomes (11)

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1 Source: National Diabetes Statistics Report

Sources Mounjaro KwikPen 10mg solution for injection in pre-filled pen, emc [accessed 16 October 2025] Obesity, NHS [accessed 16 October 2025] Once-Weekly Semaglutide in Adults with Overweight or Obesity, NEJM [accessed 16 October 2025] Tirzepatide Once Weekly for the Treatment of Obesity, NEJM [accessed 16 October 2025] Wegovy 0.25 mg, FlexTouch solution for injection in pre-filled pen, emc [accessed 16 October 2025] Patient Reviews Related Weight Loss Treatments Further Reading on Weight Loss Do Appetite Suppressants Work

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