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Whilst some laboratory studies and small-scale human trials have suggested that certain probiotic strains may influence gut hormone levels, there is currently no robust clinical evidence demonstrating that probiotic supplements can reliably increase GLP-1 production or lead to clinically significant weight loss in humans

Unlike diarrhea, it may persist throughout treatment if not actively managed

Several forces are working to bring GLP-1 costs down and expand access over the medium term

Retatrutide remains an investigational medication

In fact, up to 88% of people on plant-based diets may lack adequate serum vitamin B12 levels