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The review confirmed GLP-1R is expressed at high levels on -cells, where GLP-1 stimulates somatostatin secretion which in turn indirectly suppresses both glucagon and insulin through paracrine mechanisms
Considered by some to be the master antioxidant, glutathione plays a crucial role in shielding cells from oxidative stress
Future multicenter, large-sample RCTs incorporating liver transcriptomics and metabolomics are warranted to optimize dosing and treatment duration in MASLD patients with IR
Severe gastrointestinal disease gastroparesis, severe reflux, or uncontrolled IBD
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