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180 Despite these promising findings, questions remain regarding the best type, dose, and location of electrical stimulation for maximizing tinnitus relief

Oral contraceptives, which interfere with B6 metabolism, have also been associated with low levels

One important enzyme is glutathione reductase

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Hence PDI proteins play a critical role in regulating the intracellular redox state, redox signaling, and in preventing protein misfolding and/or aggregation (Wang et al., 2015)