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continued approval may be contingent on verification and description of clinical benefit in a confirmatory trial

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To this end, we first identified the top 1000 AD-associated risk genes using the MAGMA tool 54 and then scored each cell across all treatment groups for enrichment of AD-associated GWAS genes using the scDRS tool 55

In such instances, the integrity of the epithelium is compromised due to bacterial virulence factors, leading to impaired viscoelasticity of the mucus