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[10] Cisplatin is a widely used chemotherapy drug limited by nephrotoxicity

Mean body weight changes across the groups at the end of 32 weeks were: CagriSema: 15.6% Semaglutide alone: 5.1% Cagrilinitide alone: 8.1% [43] Side effects included nausea (29% of patients), diarrhea (16%) and vomiting (10%) in CagriSema treated patients

Although our point estimate may suggest a potential neutral or increased risk of MACE with combination therapy, this may reflect confounding by indication rather than a true association

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TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation