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This increased gastric distension can promote the reflux of stomach contents back into the oesophagus, particularly when lying down or bending over

However, this rapid pharmacokinetic profile is also associated with a higher potential for misuse and dependence compared with longer-acting benzodiazepines

RSL-3 blocks GPX4, which increases the levels of ROS and malondialdehyde (MDA) inside cells and promotes ferroptosis by blocking the SLC7A11/GSH/GPX4 pathway (73)

Patients should contact their healthcare provider if gastrointestinal side effects do not improve after 68 weeks at a stable dose, as this may indicate poor tolerance requiring dose adjustment or medication discontinuation

Supports the liver's natural detoxification*