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Summary: Retatrutide may modestly reduce blood pressure as part of its broader cardiometabolic effects, but it remains an investigational medicine not yet licensed in the UK, and its full cardiovascular profile has not been established
Data from nationwide registers from Sweden, Denmark and Norway showed that patients initiating SGLT-2i were less likely to develop renal adverse events, such as RRT, hospitalization, or death for renal causes, compared to GLP-1RA users [37]
The safer approach is to contact the prescribing clinician before changing the dose
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