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[13] In a newly diagnosed vitamin B 12 -deficient patient, normally defined as when serum levels are less than 200 pg/ml, daily IM injections of hydroxocobalamin up to 1,000 g (1 mg) per day are given to replenish the body's depleted cobalamin stores

National Institutes of Health lists the characteristics of B12 deficiency as: megaloblastic anemia (abnormally large and immature red blood cells) fatigue constipation loss of appetite neurological issues, such as difficulty with balance, depression, and confusion Certain people might also be more likely to need a vitamin B12 supplement: If youre vegan or vegetarian If you follow a vegetarian or vegan diet, youre at a higher risk of a vitamin B12 deficiency since meat, eggs, poultry, and other dairy animal products are the main sources of B12

Furukawa S et al

Scientific References TripleHormone-Receptor Agonist Retatrutide for Obesity (Jastreboff et al.)

Your medical provider will help determine the best schedule for you