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Last reviewed: July 7, 2026 Last updated: July 7, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Increasing Calorie Burning In addition to curbing appetite, Semaglutide also boosts metabolism, helping your body burn more calories throughout the day

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TRIUMPH-4 (knee osteoarthritis, Dec 2025) 28.7% weight loss

Experiencing Side Effects and Adjusting to the Medication During the first few weeks on Semaglutide, I did experience some side effects