Zamorskii II, Shchudrova TS, Zeleniuk VG, Linkova NS, Nichik TE, Khavinson VK (2019)
Start your intake Why Does Tirzepatide Cause Body Soreness
MOF were defined as hip, vertebral, humerus, or forearm fractures
In November 2025, 12% of adults reported that they were taking a GLP-1 drug a 6% increase from 18 months earlier, KFF reported
Annualized cost comparisons in 2026: Bariatric surgery (gastric sleeve or bypass): ,000 to ,000 one-time, often covered by insurance for severe obesity Wegovy at list price: about ,200 per year Zepbound at list price: about ,720 per year Compounded semaglutide (legitimate US pharmacy): ,800 to ,000 per year Compounded tirzepatide: ,000 to ,000 per year Retatrutide at launch will likely fit in the Wegovy/Zepbound range at list price, with significantly lower out-of-pocket cost for insured patients with savings card eligibility