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Monitoring parameters during treatment should include regular assessment of therapeutic response, adverse effects, and relevant laboratory parameters

These individuals need supplementation and regular monitoring to prevent deficiency from developing over months to years of treatment

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Common applications include: Obesity and Body-Weight Regulation Models : Studying how chronic exposure to AOD 9604 affects body weight, fat, and energy use in obese rodents, often using calorimetry (measuring energy expenditure) and body fat measurements