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However, they also say that a decent amount of muscle loss is par for the course for anyone losing weight rapidly, specifically highlighting those who have had bariatric surgery, and not necessarily specific to GLP-1s
For patients in these risk groups, adding an SGLT-2 inhibitor should be considered
It may still work to regulate blood sugar, but the appetite suppressant effect wanes with continued use
Ethical approval was not required for this systematic review, as it uses publicly available, de-identified data from ClinicalTrials.gov without direct patient interaction
[2] Walker, E., Lo, K., & Gopal, P
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