consumers with modest metabolic goals seeking 5-10% body weight reduction over 6-12 months rather than the 15-20% documented in pharmaceutical trials
Sometimes we see patients say, OK, Im just going to take this medication, or Im just going to do this surgery, and I really dont have to change what Im doing, and they tend to be much less successful. People with obesity or who are overweight still have success losing weight on Zepbound, the brand name version of tirzepatide, regardless of other obesity-related conditions like hypertension
Current evidence is derived primarily from preclinical studies and a limited number of clinical trials, which may not fully represent the diverse HFpEF population
The FDA announced a shortage of Adderall in October, noting that Teva Pharmaceuticals, the countrys largest Adderall producer, was experiencing manufacturing delays
(The mast cell paper mentioned several obese patients who tolerated the standard dose quite well.) Still, its a big risk as Dr