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Based on the results of the submitted ITC oral semaglutide both as second- and third-line therapy is likely better than placebo and the results suggest potential superiority to other treatment classes, specifically SGLT-2, DPP-4 inhibitors, TZD, and SUs
A researcher planning a dosing protocol around a labeled 10mg vial who is actually working with 5.7mg of tirzepatide is not running the experiment they think they are running
Evidence indicates that sulfonylureas, DPP-4 inhibitors, SGLT2 inhibitors, and insulin improve -cell incretin sensitivity in humans
The subjects were randomly assigned to receive subcutaneous semaglutide at doses of 0.5 mg or comparator medications (placebo, sitagliptin, exenatide extended-release, or insulin glargine)
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