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Furthermore, our results can be generalised mostly to individuals with type 2 diabetes who are already on metformin-based background therapy, given that drug-naive individuals were recruited only in one study [22]

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4.2 MI and ovarian function: oocyte maturation, follicular fluid microenvironment, and FSH signaling MI plays a pivotal role in ovarian physiology, exerting effects on oocyte maturation, modulation of the follicular fluid microenvironment, and enhancement of follicle-stimulating hormone (FSH) signaling

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