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LP-BM5-infected mice treatment with GSH replacement changed the macrophage polarization to M1 profile, inducing an increase in Th1 cytokine production and augmented antiviral response [38]

165 Hormone Therapies Estrogen fluctuations appear to coincide with times of increased pain sensitivity in women, but little is known about the role of estrogen and progesterone therapy in treating fibromyalgia

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Our findings revealed that Gstp gene knocked caused a significant increase in mouse serum HMGB1 level, suggesting that GSTP might function as a negative regulator in controlling HMGB1 release in sepsis