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Lee et al., 2024)
Evidence has shown their capability to increase the expression of NRF2 target genes in cellular and in vivo models of chronic obstructive pulmonary disease (COPD) [298], and to interfere with the direct PPI between KEAP1 and NRF2 or the PPI between KEAP1 and CUL3 [299, 300]
Since routine mammography has already been introduced in most countries, an earlier diagnosis due to stricter adherence to mammography would have to be suggested
Tirzepatide-based medications like Zepbound trigger weight loss through dual GLP-1 and GIP receptor activation, but some patients experience headaches during the first weeks of treatment
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