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Researchers at the University of Texas Medical Branch first characterized 5-amino-1mq in 2017 while searching for ways to inhibit NNMT, an enzyme they had identified as a key regulator of fat cell metabolism

Peripherally, pancytopenia is most often observed, but only 12 of the major cell types (erythrocytes, leukocytes, platelets) may be depressed in some cases

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HSL residue numbering differs across species and protein isoforms