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Ipamorelin's human data is limited to two published pharmacokinetic/pharmacodynamic studies: a 1999 PK/PD study (PMID: 10496658) that documented dose-response relationships and peak GH at 30-40 minutes post-injection in human volunteers, and a completed Phase II clinical trial for postoperative ileus (NCT00672074), after which ipamorelin's development for this indication was discontinued without approval
"We believe that if even a single patient feels the need to turn to potentially unsafe and unapproved knockoff alternatives, that's one too many." The company noted in its second-quarter earnings call this month that compounding pharmacies, which are allowed to make versions of medications approved by the U.S
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