Tailored Treatment: The dosage and form of B12 supplementation will always be tailored to your specific needs, the severity of your deficiency, and its root cause
Main clinical features of vitamin B12 (cobalamin) deficiency [1,2,5] Table 2
The type of treatment a person needs will depend on the underlying cause of their deficiency
In a study of 10 healthy male volunteers, omeprazole, in doses of 20 mg40 mg per day, caused a significant decrease in the oral absorption of methylcobalamin, vitamin B12
Investigation Areas Enzyme inhibition/interaction screening (in vitro) Pathway signaling and downstream readouts Solubility, vehicle selection, and excipient compatibility Stability studies (temperature/light/oxidation)