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During the initial stages of exercise, glycogen stores quickly diminish and so the body is forced to find an alternate source of energy, which it gets in the form of body fat
The gradual escalation serves two purposes: it allows the body to adapt to GLP-1 receptor activation (reducing nausea), and it permits glucagon receptor effects to build progressively without overwhelming metabolic pathways
Glucagon-like peptide-1, or GLP-1, is a naturally occurring intestinal hormone involved in glucose regulation, appetite, and digestion
(2018) 91:e13942
Recent attention in the field of glucagon research has highlighted its potential for inducing weight loss in obese patients through mechanisms like lipolysis, thermogenesis, and enhanced energy metabolism [103]
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