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In another investigation, Diamond et al
Based on current evidence, GLP-1RAs are not recommended as first-line therapy for type 2 diabetic patients at high risk for colorectal cancer [47]
Marfella R et al (2022) Does poor glycaemic control affect the immunogenicity of the COVID-19 vaccination in patients with type 2 diabetes: The CAVEAT study
Certain patients benefit most from GLP-1 treatment despite reproductive considerations: those with type 2 diabetes requiring glucose control, patients with significant metabolic disease, or individuals for whom weight management provides substantial health benefits
This means dose increases do not produce immediate full effects
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