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R., Gan E., Darbandi R., Yoon S.-Y., Wu J
PubMed Central , NeuroImage
Consequently, a significant proportion of administered nanocarriers is prematurely sequestered and cleared by the reticuloendothelial system (RES)particularly the liver and spleensubstantially limiting the effective dose that reaches the osteosarcoma TME (69, 70)
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