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Because of the safety concerns and lack of approval, it should be approached with caution and medical guidance

Furthermore, GLP-1 has beneficial cardiovascular effects in humans by lowering blood pressure and improving myocardial function [20, 21], although in rats this peptide significantly increases arterial blood pressure and heart rate [22, 23]

GLP-1 was discovered in the 1980s, and GLP-1RAs have been around for about 20 years (the first one approved for humans was a synthetic version of a molecule isolated from the venom of Gila monsters), but recent development of new versions of this type of drug are revolutionising treatment of diabetes and obesity

Pharma companies are already combing through the latest genetic research looking for ways to better define their drugs target demographics

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