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With Semaglutide, many patients lose up to 10 pounds every 46 weeks, gain control over emotional eating, and experience improved energy and confidence

Candidates like Eli Lillys retatrutide and Amgens MariTide are raising the bar, with Phase II trials showing weight loss exceeding 24%, a level comparable to that achieved with bariatric surgery

Thus, the carnitine pool plays a key role in maintaining endocrine homeostasis and metabolic health and provides a new therapeutic strategy for the treatment of some reproductive and metabolic diseases

Participants were randomized to semaglutide 2.4 mg per week or placebo

It is critically important to emphasise that because retatrutide does not currently hold a licence for use in the UK, there is no officially approved prescribing guidance from NICE or the MHRA